Research Focus Areas

The promise of our targets

We approach discovery with an entrepreneurial spirit and choose to pursue targets based on where we believe the science will take us in the next decade, not just a few years from now. Our clinical research and development spans multiple areas, including oncogenic pathways, survival mechanisms, and novel protein interactions.

We invite you to explore our current focus areas below:

Redox balance and pSTAT3

The prognostic value of pSTAT3 in cancer may be connected to redox balance.

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MCL-1 dependency

CDK9 inhibition may be a therapeutic strategy for some MCL-1-dependent hematologic malignancies.

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Wilms’ tumor 1 (WT1)

WT1 is a highly prioritized tumor antigen that may be a candidate for immunotherapy approaches.

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Cancer metabolism and PKM2

Tumor cell metabolism and immune evasion may be dependent on the dynamic and targetable properties of PKM2.

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